## Survival Analysis

A 2-Day Seminar taught by Paul D. Allison, Ph.D.

**For event-time data, ordinary regression analysis won’t do the job.**

If you’ve ever used regression analysis on longitudinal event data, you’ve probably come up against two intractable problems:

**Censoring**: Nearly every sample contains some cases that do not experience an event. If the dependent variable is the time of the event, what do you do with these “censored” cases?**Time-dependent****covariates**: Many explanatory variables (like income or blood pressure) change in value over time. How do you put such variables in a regression analysis?

Makeshift solutions to these questions can lead to severe biases. Survival methods are explicitly designed to deal with censoring and time-dependent covariates in a statistically correct way. Originally developed by biostatisticians, these methods have become popular in sociology, demography, psychology, economics, political science, and marketing.

**How you will benefit from this seminar**

Survival Analysis covers both the theory and practice of survival methodology. Assuming no previous knowledge of survival analysis, this course will turn you into a knowledgeable and skilled user of these indispensable techniques. Here are a few of the skills you will acquire:

- How to organize survival data.
- How to choose the right time axis.
- When to use discrete vs. continuous time methods.
- What to do about nonproportionality.
- How to compute R-squared.
- When and how to correct for unobserved heterogeneity.
- How frequently to measure independent variables.
- What to do if there is more than one kind of event.
- How to test for sensitivity to informative censoring.

This is a hands-on course with ample opportunity for participants to practice survival analysis.

### COMPUTING

This is a hands-on course with at least one hour each day devoted to carefully structured and supervised assignments. **To do the exercises, you will need to bring your own laptop computer with either SAS or Stata installed**. Power outlets will be provided at each seat.

For Stata users,** **version 14 will be used for the examples, but the exercises can also be done with versions 12 or 13. Seminar participants who are not yet ready to purchase Stata could take advantage of StataCorp’s free 30-day evaluation offer or their 30-day software return policy.

There is now a free version of SAS, called the SAS University Edition, that is available to anyone. It has everything needed to run the exercises in this course, and it will run on Windows, Mac or Linux computers. However, you do need a 64-bit machine with at least 1 GB of RAM. You also have to download and install virtualization software that is available free from third-party vendors. The SAS Studio interface runs in your browser, but you do not have to be connected to the Internet. The download and installation are a bit complicated, but well worth the time and effort.

### Who should attend

If you need to analyze longitudinal event data and have a basic statistical background, this seminar is for you. You should have a good working knowledge of the principles and practice of multiple regression, as well as elementary statistical inference. But you do not need to know matrix algebra, calculus, or likelihood theory.

Previous participants have come from a wide variety of fields: sociology, demography, psychology, economics, management, finance, history, marketing, biology, medicine, veterinary medicine and criminal justice.

### Location, Format, AND Materials

The seminar meets Friday, October 28 and Saturday, October 29 at the Manhattan Beach Marriott 1400 Parkview Avenue Manhattan Beach, California 90266.

The class will meet from 9 to 5 each day with a 1-hour lunch break.

Participants receive a bound manual containing detailed lecture notes (with equations and graphics), examples of computer printout, and many other useful features. This book frees participants from the distracting task of note taking.

### Registration and lodging

The fee of $995.00 includes all seminar materials.

**Lodging Reservation Instructions**

A block of rooms has been reserved at the Manhattan Beach Marriott 1400 Parkview Avenue Manhattan Beach, California 90266 at a special rate of $169 per night. In order to guarantee rate and availability, make your reservations by calling Marriott Reservation 1 (888) 236 2427 or 1 (310) 546-7511 no later than**, Thursday, October 6, 2016** and identify yourself as part of the Statistical Horizons Meeting group.

### SEMINAR OUTLINE

- Fundamentals of Survival Analysis
- Problems with conventional methods
- Types of censoring
- Kaplan-Meier estimation
- Proportional hazards models
- Partial likelihood estimation
- Interpretation of parameters
- Competing risks
- Time dependent covariates
- Discrete time analysis
- Sensitivity analysis for censoring
- Choice of time axis
- Testing the proportional hazards assumption
- Stratification
- Heterogeneity and time dependence
- Repeated events
- Left censoring, left truncation

### RECENT COMMENTS FROM PARTICIPANTS

“This course defines FANTASTIC! I’m so impressed by all of what we were able to cover in just two days. The value of the course is, well, invaluable. I will definitely be signing up for other courses and telling everyone about Statistical Horizons!”

*Valerie Stackman, University of Wisconsin-Platteville*

“This course provides a great introduction to Survival Analysis. The materials are excellent, complete with syntax for running models. This will definitely set me up for designing my methodology for my dissertation.”

* Ann Kellogg, University of Maryland*

“This class is a very good crash course in survival analysis. I was relatively new to the subject, and I feel like I am leaving with a good amount of knowledge that I can later apply in my job setting.”

* Brittany Deane, VA Boston Healthcare System*

“Survival analysis course with Paul helped me grasp the topic in great detail capturing both the theoretical and practical aspects of the topic. I thoroughly enjoyed the seminar. Paul clearly articulates the motivation assumption, code and interpretation of proportional hazard models. Given Paul’s familiarity and experience, I really appreciated Paul’s insightful observation around which methods are appropriate under specific scenarios.”

* Rahul Sharma, Capital One*

“This is a very nice course for beginners and intermediate level students. The supplied course material is self-explanatory with worked out examples – both in SAS and Stata. I found Professor Paul Allison a very experienced expert in subject matters and has a brilliant technique to unfold complicated mathematical concepts in a simple way – that’s a game changer.”

* Kamal KC, State Farm Insurance Company*

“Paul manages to fit a comprehensive overview of survival analysis into the two-day course, neither focusing too much on introductory materials or more advanced theory. There is also good balance of discussion of intuition for methods (for the less technically inclined) and theory (e.g., the separability of likelihood functions in PH models). I did not know much about survival analysis, but could code KM analysis in Excel at the end, and had good comfort with Cox/PH modeling in Stata. Overall, I took away immediately applicable information from the course.”

* Tom O’Connell, Medicus Economics, LLC*

“Dr. Allison makes the material extremely easy to understand. The materials provided in the seminar are extremely useful for attendees both at and after the seminar. Even though I use Survival Analysis with moderate frequency in my career, I was surprised at how many new things I learned during the seminar with Statistical Horizons.”

* Grettel Castro, Florida International University*